Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 3/20 | 0.46 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274211 | 0.89 | PYGL (0.43) | PYGLNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11272719 | 0.88 | ITGB1 (0.45) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL11279223 | 0.83 | MEN1 (0.48) | NPC1RAB9ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL8658843 | 0.81 | MEN1 (0.51) | NPC1RAB9APOLBPKMLMNA | |
| SCHEMBL11267025 | 0.80 | HTT (0.48) | PYGLEPHB3NPC1RAB9APOLB | |
| SCHEMBL11282702 | 0.79 | PYGL (0.48) | PYGLEPHB3TDP1NPC1RAB9A | |
| SCHEMBL11276626 | 0.78 | NPC1 (0.49) | PYGLEPHB3NPC1RAB9APOLB | |
| SCHEMBL11282236 | 0.78 | CNR2 (0.48) | PYGLEPHB3TDP1NPC1RAB9A | |
| SCHEMBL11281409 | 0.78 | PYGL (0.44) | PYGLEPHB3TDP1NPC1RAB9A | |
| SCHEMBL8669219 | 0.77 | GAA (0.46) | PYGLEPHB3TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |