Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285219 | 0.89 | PYGL (0.46) | PYGLSMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL11272719 | 0.81 | ITGB1 (0.45) | SMN1; SMN2HPGDLMNAHTTATM | |
| SCHEMBL11276064 | 0.81 | HTT (0.46) | PYGLSMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL8658843 | 0.80 | MEN1 (0.51) | SMN1; SMN2LMNAATMNPC1RAB9A | |
| SCHEMBL11285295 | 0.78 | CNR2 (0.47) | PYGLLMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11273034 | 0.77 | SMN1; SMN2 (0.41) | PYGLSMN1; SMN2HPGDHTTNPC1 | |
| SCHEMBL11279223 | 0.77 | MEN1 (0.48) | LMNANPC1RAB9AKDM4EGAA | |
| SCHEMBL11271650 | 0.76 | RXFP1 (0.46) | SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL11276626 | 0.72 | NPC1 (0.49) | PYGLSMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL11267025 | 0.70 | HTT (0.48) | PYGLSMN1; SMN2HPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |