Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267025 | 0.91 | HTT (0.48) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL11277938 | 0.88 | PTGES (0.52) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL11282702 | 0.88 | PYGL (0.48) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL11276064 | 0.85 | HTT (0.46) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL11283690 | 0.85 | PYGL (0.45) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL8669219 | 0.83 | GAA (0.46) | NPC1MAPTKDM4EHTTCYP1A2 | |
| SCHEMBL11283145 | 0.81 | MAPK14 (0.47) | MAPTALDH1A1HTTCYP1A2CYP2C9 | |
| SCHEMBL11278901 | 0.79 | HTT (0.46) | NPC1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL11285219 | 0.78 | PYGL (0.46) | NPC1MAPTALDH1A1POLBHPGD | |
| SCHEMBL9135913 | 0.77 | GAA (0.45) | NPC1MAPTALDH1A1HTTPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |