Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279223 | 0.93 | MEN1 (0.48) | ITGB1ITGA4ITGB7LMNAMEN1 | |
| SCHEMBL8658843 | 0.89 | MEN1 (0.51) | ITGB1ITGA4ITGB7SMN1; SMN2LMNA | |
| SCHEMBL11285219 | 0.88 | PYGL (0.46) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL11274211 | 0.81 | PYGL (0.43) | SMN1; SMN2LMNAHTTHPGDATM | |
| SCHEMBL11278901 | 0.80 | HTT (0.46) | ITGB1ITGA4ITGB7SMN1; SMN2LMNA | |
| SCHEMBL11273766 | 0.79 | SMN1; SMN2 (0.47) | ITGB1ITGA4ITGB7SMN1; SMN2LMNA | |
| SCHEMBL11277938 | 0.78 | PTGES (0.52) | ITGB1ITGA4ITGB7SMN1; SMN2LMNA | |
| SCHEMBL11277269 | 0.78 | NPC1 (0.56) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL11278294 | 0.77 | CNR2 (0.49) | ITGB1ITGA4ITGB7SMN1; SMN2MEN1 | |
| SCHEMBL11277798 | 0.77 | ITGB1 (0.43) | ITGB1ITGA4ITGB7SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |