Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282060 | 0.98 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1FFAR4 | |
| SCHEMBL7394128 | 0.86 | TDP1 (0.41) | SPHK1KMT2APTGES2 | |
| SCHEMBL7652663 | 0.81 | SPHK1 (0.46) | SPHK1SPHK2SIGMAR1FFAR4MEN1 | |
| SCHEMBL11275021 | 0.79 | SPHK1 (0.45) | SPHK1SPHK2FFAR4 | |
| SCHEMBL7650177 | 0.79 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1FFAR4 | |
| SCHEMBL11165604 | 0.79 | SPHK1 (0.61) | SPHK1SPHK2 | |
| SCHEMBL7654715 | 0.79 | SPHK1 (0.49) | SPHK1SPHK2SIGMAR1FFAR4MEN1 | |
| SCHEMBL21152607 | 0.79 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1FFAR4 | |
| SCHEMBL20793673 | 0.79 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1FFAR4 | |
| SCHEMBL11336354 | 0.79 | SPHK1 (0.71) | SPHK1SPHK2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328380-A | Substituted phenylpropyl halides | BASF AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |
| EP-0009077-B1 | SUBSTITUTED PHENYLPROPYL HALIDES, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1981-09-30 | — | — | EP | disclosed |
| US-4250123-A | CHEMICAL INTERMEDIATES FOR FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |
| EP-0009077-A1 | Substituted phenylpropyl halides, their preparation and use | BASF Aktiengesellschaft (DE) | 1980-04-02 | — | — | EP | disclosed |