Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289006 | 0.87 | LMNA (0.39) | TRPV1LMNAHTR1ADRD2DRD4 | |
| SCHEMBL11281691 | 0.85 | DRD2 (0.39) | LMNAHTR1ADRD2DRD4HTR2A | |
| SCHEMBL11287243 | 0.79 | LMNA (0.39) | TRPV1LMNAHTR1ADRD2DRD4 | |
| SCHEMBL11279680 | 0.77 | LMNA (0.37) | TRPV1LMNAHTR1ADRD2DRD4 | |
| SCHEMBL11290953 | 0.76 | TRPV1 (0.39) | TRPV1LMNAHTR1ADRD2DRD4 | |
| SCHEMBL11288979 | 0.75 | LMNA (0.42) | TRPV1LMNAHTR1ADRD2DRD4 | |
| SCHEMBL11287197 | 0.74 | SIGMAR1 (0.59) | LMNAHTR1ADRD2DRD4HTR2A | |
| SCHEMBL11227136 | 0.72 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL11284731 | 0.72 | TRPV1 (0.38) | TRPV1LMNAHTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL11288527 | 0.72 | HTR2A (0.50) | HTR1ADRD2DRD4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353900-A | HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |