Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279353 | 0.87 | SLC9A1 (0.33) | HPGDNPC1 | |
| SCHEMBL7754721 | 0.87 | ALDH1A1 (0.50) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL11274036 | 0.79 | CES2 (0.44) | ALDH1A1HPGDTDP1NPC1KMT2A | |
| SCHEMBL15540354 | 0.79 | ALDH1A1 (0.42) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL15541038 | 0.79 | TYK2 (0.44) | ALDH1A1FEN1HPGDNPC1GLA | |
| SCHEMBL4158394 | 0.79 | GAA (0.47) | ALDH1A1HPGDPOLBKMT2AJAK2 | |
| SCHEMBL7218300 | 0.76 | ALDH1A1 (0.39) | ALDH1A1FEN1HPGDL3MBTL1NPC1 | |
| SCHEMBL11566624 | 0.74 | DPP4 (0.36) | ALDH1A1FEN1TDP1POLBCYP3A4 | |
| SCHEMBL2844436 | 0.74 | ALDH1A1 (0.71) | ALDH1A1FEN1F2RHPGDTDP1 | |
| SCHEMBL696250 | 0.74 | ALDH1A1 (0.52) | ALDH1A1FEN1F2RHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |