Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754721 | 0.87 | ALDH1A1 (0.50) | GAAPBRM1JAK2JAK1TYK2 | |
| SCHEMBL4141953 | 0.87 | CES2 (0.52) | GAAJAK2JAK1TYK2CES2 | |
| SCHEMBL10875815 | 0.85 | GAA (0.46) | GAAPBRM1JAK2JAK1TYK2 | |
| SCHEMBL15541038 | 0.79 | TYK2 (0.44) | GAATYK2KMT2AALDH1A1LMNA | |
| SCHEMBL10991228 | 0.79 | CES2 (0.44) | GAACES2CES1KMT2AMEN1 | |
| SCHEMBL11286353 | 0.79 | ALDH1A1 (0.42) | JAK2JAK1TYK2KMT2AMEN1 | |
| SCHEMBL11274036 | 0.79 | CES2 (0.44) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL15540354 | 0.79 | ALDH1A1 (0.42) | GAAPBRM1JAK2JAK1TYK2 | |
| SCHEMBL7218300 | 0.76 | ALDH1A1 (0.39) | GAAJAK2JAK1TYK2ALDH1A1 | |
| SCHEMBL10646069 | 0.76 | PPIA (0.45) | GAACES2CES1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003099-B1 | N-PHENYL-N'(2-CHLORO-6-FLUORO-BENZOYL) UREA, PREPARATION THEREOF AND USE THEREOF AS INSECTICIDES | BAYER AG (DE) | 1981-09-16 | — | — | EP | claimed |
| EP-0003099-A2 | N-phenyl-N'(2-chloro-6-fluoro-benzoyl) urea, preparation thereof and use thereof as insecticides | BAYER AG (DE) | 1979-07-25 | — | — | EP | claimed |
| US-10821100-B2 | Triazolone compounds as mPGES-1 inhibitors | Ichnos Sciences SA (CH) | 2020-11-03 | — | — | US | disclosed |
| US-10821100-B2 | Triazolone compounds as mPGES-1 inhibitors | Ichnos Sciences SA (CH) | 2020-11-03 | — | — | US | disclosed |
| US-20190282548-A1 | TRIAZOLONE COMPOUNDS AS MPGES-1 INHIBITORS | Ichnos Sciences SA (CH) | 2019-09-19 | — | — | US | disclosed |
| US-20190282548-A1 | TRIAZOLONE COMPOUNDS AS MPGES-1 INHIBITORS | Ichnos Sciences SA (CH) | 2019-09-19 | — | — | US | disclosed |
| US-10391083-B2 | Triazolone compounds as MPGES-1 inhibitors | GLENMARK PHARMACEUTICALS S.A (CH) | 2019-08-27 | — | — | US | disclosed |
| US-10391083-B2 | Triazolone compounds as MPGES-1 inhibitors | GLENMARK PHARMACEUTICALS S.A (CH) | 2019-08-27 | — | — | US | disclosed |
| US-20180200229-A1 | TRIAZOLONE COMPOUNDS AS MPGES-1 INHIBITORS | Ichnos Sciences SA (CH) | 2018-07-19 | — | — | US | disclosed |
| US-20180200229-A1 | TRIAZOLONE COMPOUNDS AS MPGES-1 INHIBITORS | Ichnos Sciences SA (CH) | 2018-07-19 | — | — | US | disclosed |
| US-9949955-B2 | Triazolone compounds as mPGES-1 inhibitors | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-04-24 | — | — | US | disclosed |
| EP-0003099-B1 | N-PHENYL-N'(2-CHLORO-6-FLUORO-BENZOYL) UREA, PREPARATION THEREOF AND USE THEREOF AS INSECTICIDES | BAYER AG (DE) | 1981-09-16 | — | — | EP | disclosed |
| EP-0009762-B1 | SUBSTITUTED N-BENZOYL-N'-TERT.-ALCOXYCARBONYLPHENYL(THIO)UREAS, METHODS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1981-08-05 | — | — | EP | disclosed |
| EP-0033231-A1 | Insecticidal compositions containing 2,6-dihalobenzoylurea derivatives | ELI LILLY AND COMPANY (US) | 1981-08-05 | — | — | EP | disclosed |
| US-4281003-A | 1-(2-6-Dihalobenzoyl)-3-(5-substituted-2-pyridinyl)urea insecticides and insecticidal method | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4277499-A | Combating insects with N-(substituted-phenyl)-N-(2-chloro-6-fluoro-benzoyl)-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| US-4234600-A | Combating arthropods with N-benzoyl-N'-tert.-alkoxycarbonylphenyl-(thio) ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-18 | — | — | US | disclosed |
| EP-0009762-A1 | Substituted N-benzoyl-N'-tert.-alcoxycarbonylphenyl(thio)ureas, methods for their preparation and their use as insecticides | BAYER AG (DE) | 1980-04-16 | — | — | EP | disclosed |
| EP-0003099-A2 | N-phenyl-N'(2-chloro-6-fluoro-benzoyl) urea, preparation thereof and use thereof as insecticides | BAYER AG (DE) | 1979-07-25 | — | — | EP | disclosed |
| EP-0003099-A2 | N-phenyl-N'(2-chloro-6-fluoro-benzoyl) urea, preparation thereof and use thereof as insecticides | BAYER AG (DE) | 1979-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282548-A1 | TRIAZOLONE COMPOUNDS AS MPGES-1 INHIBITORS | PTGES, PTGS1, PTGIS | GAA 1319/4885PBRM1 3922/4885JAK2 1888/4885 |
| US-10391083-B2 | Triazolone compounds as MPGES-1 inhibitors | PTGES, PTGS1, PTGIS | GAA 1319/4885PBRM1 3922/4885JAK2 1888/4885 |
| US-20180200229-A1 | TRIAZOLONE COMPOUNDS AS MPGES-1 INHIBITORS | PTGES, PTGS1, PTGIS | GAA 1319/4885PBRM1 3922/4885JAK2 1888/4885 |
| US-10821100-B2 | Triazolone compounds as mPGES-1 inhibitors | PTGES, PTGS1, PTGIS | GAA 1319/4885PBRM1 3922/4885JAK2 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.