Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290092 | 0.94 | LMNA (0.57) | MEN1LMNAKMT2APOLBDRD3 | |
| SCHEMBL11289689 | 0.94 | POLB (0.67) | MEN1LMNAKMT2APOLBDRD3 | |
| SCHEMBL11280042 | 0.90 | LMNA (0.74) | MEN1LMNAKMT2APOLBDRD3 | |
| SCHEMBL11431119 | 0.86 | DRD3 (0.60) | MEN1LMNAKMT2APOLBDRD3 | |
| SCHEMBL11286122 | 0.85 | DRD3 (0.56) | MEN1LMNAKMT2APOLBDRD3 | |
| Hydrochloric Acid SCHEMBL11156556 | 0.85 | ALDH1A1 (0.60) | MEN1LMNAKMT2APOLBDRD3 | |
| Fluprazine SCHEMBL2110425 | 0.83 | DRD2 (0.62) | LMNAPOLBDRD3DRD2SIGMAR1 | |
| SCHEMBL8272365 | 0.83 | ALDH1A1 (0.63) | MEN1LMNAKMT2APOLBDRD3 | |
| Fluprazine SCHEMBL29445768 | 0.83 | DRD2 (0.62) | LMNAPOLBDRD3DRD2SIGMAR1 | |
| SCHEMBL11288750 | 0.83 | DRD2 (0.58) | MEN1LMNAKMT2APOLBDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048045-A1 | Phenyl piperazine derivatives having antiagressive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-03-24 | — | — | EP | disclosed |