Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
| ▸ | DRD3 | P35462 | 5/20 | 0.63 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286375 | 0.94 | MEN1 (0.59) | POLBSIGMAR1DRD3DRD2LMNA | |
| SCHEMBL11290092 | 0.92 | LMNA (0.57) | POLBSIGMAR1DRD3DRD2LMNA | |
| SCHEMBL11280042 | 0.88 | LMNA (0.74) | POLBDRD3LMNAKMT2AMEN1 | |
| SCHEMBL11431119 | 0.86 | DRD3 (0.60) | POLBSIGMAR1DRD3DRD2LMNA | |
| SCHEMBL11286122 | 0.85 | DRD3 (0.56) | POLBSIGMAR1DRD3DRD2LMNA | |
| Hydrochloric Acid SCHEMBL11156556 | 0.85 | ALDH1A1 (0.60) | POLBSIGMAR1DRD3DRD2LMNA | |
| SCHEMBL8272367 | 0.85 | DRD3 (0.60) | POLBSIGMAR1DRD3DRD2LMNA | |
| Fluprazine SCHEMBL2110425 | 0.83 | DRD2 (0.62) | POLBSIGMAR1DRD3DRD2LMNA | |
| Fluprazine SCHEMBL29445768 | 0.83 | DRD2 (0.62) | POLBSIGMAR1DRD3DRD2LMNA | |
| SCHEMBL8272365 | 0.83 | ALDH1A1 (0.63) | POLBSIGMAR1DRD3DRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048045-A1 | Phenyl piperazine derivatives having antiagressive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-03-24 | — | — | EP | disclosed |