Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PPIG | Q13427 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286533 | 1.00 | GAA (0.50) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL7089973 | 0.79 | GAA (0.61) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL5854855 | 0.78 | EGLN1 (0.70) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL48270 | 0.77 | GAA (0.59) | GAAMGAMSIMGAM2PPID | |
| SCHEMBL27434109 | 0.77 | GAA (0.59) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL28036731 | 0.75 | ALDH1A1 (0.44) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL7946756 | 0.74 | PPID (0.62) | GAAMGAMSIMGAM2PPID | |
| SCHEMBL3409989 | 0.74 | MAPT (0.47) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL11180930 | 0.74 | TET2 (0.59) | GAAMGAMSIMGAM2EGLN1 | |
| SCHEMBL5656847 | 0.74 | MAPT (0.47) | GAAMGAMSIMGAM2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315939-A | Piperidine derivatives of 4,5-dialkyl-3-hydroxy-pyrrole-2-carboxylic acid esters, pharmaceutical formulations containing these compounds and use in treating cardiac arrhythmias | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | disclosed |