Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409989 | 1.00 | MAPT (0.47) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL28036731 | 0.80 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL20045209 | 0.79 | MAPT (0.41) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL5611950 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL5611940 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL11141816 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL9397981 | 0.77 | MAPT (0.50) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL1132073 | 0.75 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL11150815 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAHSD17B10GLO1 | |
| SCHEMBL29134075 | 0.75 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAHSD17B10GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214813-B2 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214813-B2 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-20040242889-A1 | Preparation of chiral cyclic amino acids and derivatives | THE PENN STATE RESEARCH FOUNDATION | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242889-A1 | Preparation of chiral cyclic amino acids and derivatives | AADAT, PAM, BCAT2 | MAPT 3985/4885ALDH1A1 2383/4885LMNA 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.