Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292499 | 0.90 | PDE5A (0.41) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11108141 | 0.87 | L3MBTL1 (0.47) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11287858 | 0.86 | KDM4E (0.46) | MAPTBRD4EGFRERBB2ERBB4 | |
| SCHEMBL11101546 | 0.86 | DRD2 (0.45) | MAPTBRD4EGFRERBB2ERBB4 | |
| SCHEMBL11101829 | 0.86 | KMT2A (0.47) | L3MBTL1MAPTBRD4EGFRERBB2 | |
| SCHEMBL11107673 | 0.85 | LMNA (0.41) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11287764 | 0.85 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11105712 | 0.85 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11281520 | 0.84 | PDE5A (0.35) | BRD4EGFRERBB2ERBB4PDE5A | |
| SCHEMBL11100914 | 0.84 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1BRD4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |