Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100661 | 0.90 | PPARD (0.41) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11105712 | 0.87 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11286552 | 0.87 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11287764 | 0.87 | L3MBTL1 (0.44) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11111031 | 0.85 | L3MBTL1 (0.43) | L3MBTL1MAPTNPSR1BRD4EGFR | |
| SCHEMBL11104973 | 0.85 | KDM4E (0.47) | MAPTBRD4EGFRERBB2ERBB4 | |
| SCHEMBL11109252 | 0.85 | DRD2 (0.47) | MAPTBRD4EGFRERBB2ERBB4 | |
| SCHEMBL11102123 | 0.83 | MEN1 (0.47) | L3MBTL1MAPTBRD4EGFRERBB2 | |
| SCHEMBL11106513 | 0.81 | LMNA (0.45) | L3MBTL1MAPTBRD4EGFRERBB2 | |
| SCHEMBL11254421 | 0.81 | LDHA (0.65) | MAPTNPSR1BRD4EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |