Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824889 | 0.84 | MEN1 (0.45) | MEN1KMT2ATSHRGAACSNK2A1 | |
| SCHEMBL16590409 | 0.82 | CPS1 (0.39) | MEN1KMT2ATSHRCSNK2A1SMN1; SMN2 | |
| SCHEMBL4936719 | 0.77 | ERCC5 (0.46) | KMT2ATSHRSMN1; SMN2NPC1HPGD | |
| SCHEMBL30341583 | 0.76 | MEN1 (0.47) | MEN1KMT2ATSHRGAACSNK2A1 | |
| SCHEMBL11912035 | 0.76 | MEN1 (0.47) | MEN1KMT2ATSHRGAACSNK2A1 | |
| SCHEMBL9862051 | 0.73 | MEN1 (0.57) | MEN1KMT2ATSHRGAACSNK2A1 | |
| SCHEMBL9420245 | 0.73 | MEN1 (0.57) | MEN1KMT2ATSHRGAACSNK2A1 | |
| Hydrochloric Acid SCHEMBL8393812 | 0.73 | SLC9A1 (0.53) | CYP2D6 | |
| SCHEMBL811028 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2AGAASMN1; SMN2NPC1 | |
| SCHEMBL27601016 | 0.71 | MEN1 (0.40) | MEN1KMT2ATSHRGAACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047496-A1 | Sulfonyl ureas, processes for their production, pharmaceutical compositions based on these compounds and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-17 | — | — | EP | disclosed |