SCHEMBL11287142

SCHEMBL11287142

CC(=O)Oc1ccc(OC(F)(F)Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
MAPT P10636 4/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
ELANE P08246 3/20 0.47
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 1/20 0.46
GAA P10253 2/20 0.44
HSP90AA1 P07900 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP3A4 P08684 2/20 0.43
TTR P02766 1/20 0.43
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GLA P06280 1/20 0.42
FAAH O00519 1/20 0.41
EPHX2 P34913 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3960405 0.84 LMNA (0.57) LMNAMAPTPOLBPKMELANE
SCHEMBL9171972 0.79 LMNA (0.52) LMNAMAPTPOLBPKMELANE
SCHEMBL269329 0.78 LMNA (0.80) LMNAMAPTPOLBPKMELANE
SCHEMBL8080539 0.78 LMNA (0.59) LMNAMAPTPOLBPKMELANE
SCHEMBL9526748 0.77 ALDH1A1 (0.61) LMNAMAPTALDH1A1MEN1KMT2A
Lithium SCHEMBL30522746 0.76 LMNA (0.76) LMNAMAPTPOLBPKMELANE
SCHEMBL14760365 0.76 LMNA (0.76) LMNAMAPTPOLBPKMELANE
SCHEMBL839809 0.76 KIF11 (0.59) LMNAMAPTPOLBPKMELANE
SCHEMBL10504945 0.76 LMNA (0.57) LMNAMAPTPOLBPKMELANE
SCHEMBL10910722 0.74 ALDH1A1 (0.47) MAPTALDH1A1HSD17B10TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0063873-A1 Haloalkoxy-substituted diphenyl ethers; their use as herbicides and in herbicidal compositions and processes of making them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-11-03 EP disclosed