Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28904971 | 0.98 | ALOX15 (0.44) | ALOX15LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL28525251 | 0.98 | ALOX15 (0.44) | ALOX15LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL29163515 | 0.98 | ALOX15 (0.44) | ALOX15LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL13617276 | 0.93 | ALOX15 (0.48) | ALOX15LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL225621 | 0.84 | LMNA (0.48) | ALOX15LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL2746597 | 0.81 | TSHR (0.52) | ALOX15LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL5831644 | 0.80 | LMNA (0.39) | ALOX15LMNAHSD17B10TSHRCHRM2 | |
| SCHEMBL12933279 | 0.80 | ALDH1A1 (0.54) | LMNAHSD17B10TSHRCHRM2CHRM4 | |
| SCHEMBL28817815 | 0.79 | HTR2C (0.43) | HTR1ACYP2C19TDP1NAAACYP4F2 | |
| SCHEMBL11954968 | 0.78 | CYP4F2 (0.40) | TSHRCYP3A4TDP1NAAACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323620-A | Aromatic bridged cyclic amide derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-106536500-B | Selective matrix metalloproteinase inhibitors | 圣母大学 | 2020-01-10 | — | — | CN | disclosed |
| US-4336402-A | Process for the preparation of N-alkyl-monosubstituted carbamic acid esters | ATLANTIC RICHFIELD COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-3962302-A | Production of isocyanates from esters of carbamic acids (urethanes) | ATLANTIC RICHFIELD COMPANY (US) | 1976-06-08 | — | — | US | disclosed |