SCHEMBL28817815

SCHEMBL28817815

CC(C)(C)CCCCOC(=O)CN

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.43
NAAA Q02083 1/20 0.39
RAD52 P43351 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
FAAH O00519 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
HTR1A P08908 2/20 0.31
HTR1B P28222 2/20 0.31
CYP2C19 P33261 1/20 0.31
DGKA P23743 1/20 0.31
CYP1A2 P05177 1/20 0.31
HTR1D P28221 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18823278 0.94 HTR2C (0.41) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL16881654 0.85 HTR2C (0.35) HTR2CNAAAHTR1ACYP2C19DGKA
SCHEMBL10031825 0.83 HTR2C (0.46) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL6682800 0.82 HTR2C (0.50) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL21015283 0.80 NAAA (0.44) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL21015389 0.80 NAAA (0.44) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL11287294 0.79 ALOX15 (0.46) HTR2CNAAAPRSS1PRSS2PRSS3
Hydrochloric Acid SCHEMBL11847967 0.78 HTR2C (0.52) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL5496994 0.78 HTR2C (0.45) HTR2CNAAARAD52NPSR1FAAH
SCHEMBL28904971 0.78 ALOX15 (0.44) HTR2CNAAAHTR1ACYP2C19CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773278-A Quinazoline compound and application thereof in antivirus 苏州大学 2022-07-22 CN disclosed