SCHEMBL11287388

SCHEMBL11287388

O=c1[nH][nH]cc1Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.43
TSHR P16473 2/20 0.42
LTA4H P09960 1/20 0.42
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
ADORA2A P29274 1/20 0.40
CTNNB1 P35222 1/20 0.39
NSD2 O96028 1/20 0.39
HSP90AA1 P07900 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
TLR9 Q9NR96 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
GAPDH P04406 1/20 0.38
MAOA P21397 3/20 0.38
MAOB P27338 3/20 0.38
GSTP1 P09211 1/20 0.37
SOS1 Q07889 1/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1748619 0.73 ALDH1A1 (0.50) BRD4LMNAGAAKMT2A
SCHEMBL444631 0.69 LTA4H (0.55) TSHRLTA4HLMNAGAAKMT2A
SCHEMBL3061823 0.68 GAA (0.50) BRD4TSHRLTA4HLMNAGAA
SCHEMBL8720193 0.68 LTA4H (0.61) TSHRLTA4HLMNANSD2HSP90AA1
SCHEMBL51822 0.67 LTA4H (0.69) TSHRLTA4HLMNAGAAKMT2A
SCHEMBL1242120 0.67 KMT2A (0.41) BRD4TSHRLTA4HLMNAGAA
SCHEMBL9149133 0.65 ADORA2A (0.57) BRD4TSHRLTA4HLMNAKMT2A
SCHEMBL9264065 0.65 LTA4H (0.65) TSHRLTA4HLMNAGAAKMT2A
Bromide SCHEMBL8447011 0.65 LTA4H (0.65) TSHRLTA4HLMNAGAAKMT2A
Ammonia Solution, Strong SCHEMBL7127955 0.65 LTA4H (0.65) TSHRLTA4HLMNAGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310618-A Silver halide photographic material and process utilizing blocked dye-forming couplers EASTMAN KODAK COMPANY (US) 1982-01-12 US disclosed