Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4459446 | 0.86 | CYP3A4 (0.62) | CYP3A4CYP2C9GPR119KCNH2 | |
| SCHEMBL1128606 | 0.85 | CYP3A4 (0.78) | CYP3A4CYP2C9GPR119 | |
| SCHEMBL1128588 | 0.85 | CYP3A4 (0.70) | CYP3A4CYP2C9GPR119FLT3 | |
| SCHEMBL1128382 | 0.83 | CYP3A4 (0.63) | CYP3A4CYP2C9GPR119KCNH2 | |
| SCHEMBL1128747 | 0.83 | CYP3A4 (0.53) | CYP3A4CYP2C9GPR119EIF2AK3KCNH2 | |
| SCHEMBL1128738 | 0.80 | CYP3A4 (0.48) | CYP3A4CYP2C9GPR119KCNH2 | |
| Trifluoroacetic Acid SCHEMBL1128524 | 0.80 | CYP3A4 (0.68) | CYP3A4CYP2C9GPR119BRAFABL1 | |
| SCHEMBL9006277 | 0.80 | SRC (0.45) | CYP3A4PLK4PAK4TRPA1ABL1 | |
| SCHEMBL4354679 | 0.79 | CYP3A4 (0.57) | CYP3A4CYP2C9GPR119KDRBRAF | |
| Hydrochloric Acid SCHEMBL1128930 | 0.78 | CYP3A4 (0.41) | CYP3A4CYP2C9EIF2AK3PLK4PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188098-B2 | GPR119 receptor agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-05-29 | — | — | US | disclosed |
| EP-2283019-A1 | GPR119 RECEPTOR AGONISTS | F. Hoffmann-La Roche AG (CH) | 2011-02-16 | — | — | EP | disclosed |
| US-20090286812-A1 | GPR119 Receptor Agonists | ERICKSON SHAWN DAVID | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286812-A1 | GPR119 Receptor Agonists | GPR119, GPR27, GPR139 | CYP3A4 1503/4885CYP2C9 917/4885GPR119 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.