Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288410 | 0.93 | CYP1A2 (0.36) | CYP1A2TNFNPC1HSD17B10ALDH1A1 | |
| SCHEMBL11291816 | 0.86 | MIF (0.41) | CYP1A2NPC1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL11325392 | 0.86 | TSHR (0.43) | NPC1HSD17B10ALDH1A1TSHRKDM4E | |
| SCHEMBL11294157 | 0.84 | HTR7 (0.46) | NPC1HSD17B10ALDH1A1ALOX15TSHR | |
| SCHEMBL11288946 | 0.84 | CYP1A2 (0.41) | CYP1A2TNFNPC1ALDH1A1CYP3A4 | |
| SCHEMBL11289019 | 0.83 | HTT (0.48) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11291507 | 0.82 | PLA2G2A (0.49) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11293235 | 0.82 | CYP1A2 (0.40) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL11290793 | 0.81 | ALDH1A1 (0.47) | HSD17B10ALDH1A1ALOX15TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL11295054 | 0.81 | CYP1A2 (0.39) | CYP1A2NR1I2PGRADORA3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |