Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.68 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.68 |
| ▸ | ITGAL | P20701 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | AHR | P35869 | 1/20 | 0.68 |
| ▸ | ADK | P55263 | 1/20 | 0.68 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL27509171 | 0.92 | TRPA1 (0.74) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL5205084 | 0.92 | TRPA1 (0.74) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL27631042 | 0.92 | TRPA1 (0.74) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL8692212 | 0.90 | TRPA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL15552 | 0.90 | TRPA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL10758259 | 0.90 | TRPA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL28064106 | 0.90 | TRPA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL29160563 | 0.90 | TRPA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL384964 | 0.90 | TRPA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL23306498 | 0.89 | TRPA1 (0.59) | TRPA1CA1CA2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143455-B | Anti-cracking concrete and preparation method thereof | 廊坊泉泽混凝土有限公司 | 2025-02-11 | — | — | CN | claimed |
| US-20240350456-A1 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING INFLAMMATORY CONDITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-10-24 | — | — | US | claimed |
| CN-114438138-A | Metabolic composition prepared from clostridium sporogenes, and production method, detection method and application thereof | 重庆市畜牧科学院 | 2022-05-06 | — | — | CN | claimed |
| CN-110831943-B | Method for producing piperazine rings for the synthesis of pyrazinocarbazole derivatives | 社会医疗技术员技术股份公司 | 2022-05-03 | — | — | CN | claimed |
| EP-3612534-B1 | PROCESS FOR THE PREPARATION OF PIPERAZINE RING FOR THE SYNTHESIS OF PYRAZINOCARBAZOLE DERIVATIVES | TECNIMEDE SOCIEDADE TECNICO MEDICINAL SA (PT) | 2021-12-22 | — | — | EP | claimed |
| US-20200131186-A1 | PROCESS FOR THE PREPARATION OF PIPERAZINE RING FOR THE SYNTHESIS OF PYRAZINOCARBAZOLE DERIVATIVES | TECNIMEDE, SOCIEDADE TÉCNICO-MEDICINAL, SA (PT) | 2020-04-30 | — | — | US | claimed |
| EP-3612534-A1 | PROCESS FOR THE PREPARATION OF PIPERAZINE RING FOR THE SYNTHESIS OF PYRAZINOCARBAZOLE DERIVATIVES | Tecnimede, Sociedade Técnico-Medicinal, SA (PT) | 2020-02-26 | — | — | EP | claimed |
| CN-110831943-A | Method for producing piperazine rings for the synthesis of pyrazinocarbazole derivatives | 社会医疗技术员技术股份公司 | 2020-02-21 | — | — | CN | claimed |
| WO-2018193414-A1 | PROCESS FOR THE PREPARATION OF PIPERAZINE RING FOR THE SYNTHESIS OF PYRAZINOCARBAZOLE DERIVATIVES | TECNIMEDE, SOCIEDADE TÉCNICO-MEDICINAL, SA (PT) | 2018-10-25 | — | — | WO | claimed |
| EP-3392250-A1 | PROCESS FOR THE PREPARATION OF PIPERAZINE RING FOR THE SYNTHESIS OF PYRAZINOCARBAZOLE DERIVATIVES | TECNIMEDE-SOCIEDADE TECNICO-MEDICINAL, S.A. (PT) | 2018-10-24 | — | — | EP | claimed |
| US-6013859-A | Molecular methods of hybrid seed production | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2000-01-11 | — | — | US | claimed |
| EP-0832263-A1 | METHODS AND CONSTRUCTS FOR PRODUCING MALE STERILE PLANTS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040950-A1 | METHODS AND CONSTRUCTS FOR PRODUCING MALE STERILE PLANTS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-5426041-A | Binary cryptocytotoxic method of hybrid seed production | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1995-06-20 | — | — | US | claimed |
| EP-0540561-A1 | BINARY CRYPTOCYTOTOXIC METHOD OF HYBRID SEED PRODUCTION | PALADIN HYBRIDS INC (CA) | 1993-05-12 | — | — | EP | claimed |
| WO-1992001799-A1 | BINARY CRYPTOCYTOTOXIC METHOD OF HYBRID SEED PRODUCTION | PALADIN HYBRIDS INC. (CA) | 1992-02-06 | — | — | WO | claimed |
| US-12631644-B2 | Biomarker panel targeted to diseases due to multifactorial ontology of glycocalyx disruption | ARTEREZ, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| CN-119709703-A | Amide hydrolase mutant and application thereof | 中国农业科学院植物保护研究所 | 2025-03-28 | — | — | CN | disclosed |
| EP-0198288-A3 | TRANSFORMATION OF PLANTS TO INTRODUCE CLOSELY LINKED MARKERS | DNA Plant Technology Corporation (US) | 1986-12-17 | — | — | EP | disclosed |
| EP-0198288-A2 | Transformation of plants to introduce closely linked markers | DNA Plant Technology Corporation (US) | 1986-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12631644-B2 | Biomarker panel targeted to diseases due to multifactorial ontology of glycocalyx disruption | PGF, FGB, LGALS3BP | TRPA1 4835/4885CA1 1320/4885CA2 1600/4885 |
| US-20200131186-A1 | PROCESS FOR THE PREPARATION OF PIPERAZINE RING FOR THE SYNTHESIS OF PYRAZINOCARBAZOLE DERIVATIVES | PIR, CYP3A5, DRD5 | TRPA1 1466/4885CA1 3958/4885CA2 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.