Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977269 | 0.77 | ADRB2 (0.48) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL10977272 | 0.77 | ADRB2 (0.48) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL316151 | 0.71 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL10659126 | 0.69 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL10979422 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL10979424 | 0.69 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL159888 | 0.67 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL1402286 | 0.67 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL11664183 | 0.66 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM | |
| SCHEMBL7256881 | 0.66 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1HPGDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050558-A2 | Photographic emulsions and elements capable of forming direct-positive images | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1982-04-28 | — | — | EP | disclosed |