Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778439 | 0.76 | G6PD (0.45) | MAPTTSHRALDH1A1NAPRTKDM4E | |
| SCHEMBL27883988 | 0.76 | HSPA5 (0.58) | TSHRCYP2D6HIF1A | |
| Acetic Acid SCHEMBL28061899 | 0.75 | HSPA5 (0.47) | TSHRCYP1A2CYP2D6HIF1AKAT8 | |
| SCHEMBL20117714 | 0.72 | DAO (0.49) | ALDH1A1KDM4E | |
| SCHEMBL20117949 | 0.72 | TAAR1 (0.41) | ALDH1A1GPR84 | |
| SCHEMBL11096469 | 0.71 | ADRA2A (0.55) | MAPTALDH1A1TDP1KDM4EGAA | |
| SCHEMBL1247034 | 0.71 | TSHR (0.61) | MAPTTSHRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL79201 | 0.71 | MAOA (0.47) | ABL1SRCKAT8 | |
| SCHEMBL28180473 | 0.69 | ADRA2A (0.58) | MAPTALDH1A1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27647904 | 0.69 | DPP4 (0.47) | SLC6A2SLC6A4SLC6A3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011769-B1 | HYDROXYETHYL AZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AG (DE) | 1982-04-14 | — | — | EP | claimed |
| EP-0011769-A1 | Hydroxyethyl azoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1980-06-11 | — | — | EP | claimed |
| EP-0011769-B1 | HYDROXYETHYL AZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | BAYER AG (DE) | 1982-04-14 | — | — | EP | disclosed |
| EP-0011769-A1 | Hydroxyethyl azoles, process for their preparation and their use in medicaments | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |