Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431119 | 0.84 | DRD3 (0.60) | DRD3DRD2POLBLMNAMAPT | |
| Hydrochloric Acid SCHEMBL11156556 | 0.83 | ALDH1A1 (0.60) | DRD3DRD2POLBLMNAMAPT | |
| SCHEMBL13630154 | 0.83 | NPSR1 (0.59) | DRD3DRD2POLBLMNAMAPT | |
| SCHEMBL13630155 | 0.83 | NPSR1 (0.59) | DRD3DRD2POLBLMNAMAPT | |
| SCHEMBL4479824 | 0.83 | NPSR1 (0.59) | DRD3DRD2POLBLMNAMAPT | |
| Fluprazine SCHEMBL2110425 | 0.82 | DRD2 (0.62) | DRD3DRD2POLBLMNAMAPT | |
| SCHEMBL8272365 | 0.82 | ALDH1A1 (0.63) | DRD3DRD2POLBLMNAMAPT | |
| Fluprazine SCHEMBL29445768 | 0.82 | DRD2 (0.62) | DRD3DRD2POLBLMNAMAPT | |
| SCHEMBL11286375 | 0.81 | MEN1 (0.59) | DRD3DRD2POLBLMNAMAPT | |
| SCHEMBL11289689 | 0.81 | POLB (0.67) | DRD3DRD2POLBLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048045-A1 | Phenyl piperazine derivatives having antiagressive activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-03-24 | — | — | EP | disclosed |