Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10821151 | 0.73 | CYP1A2 (0.40) | ALDH1A1POLBCYP1A2CYP3A4TSHR | |
| SCHEMBL39726 | 0.70 | MAPT (0.49) | ALDH1A1POLBCYP1A2CYP3A4TSHR | |
| SCHEMBL11016866 | 0.67 | RPS6KA2 (0.35) | ALDH1A1POLBCYP1A2CYP3A4TSHR | |
| SCHEMBL2960834 | 0.67 | ADRB2 (0.48) | ALDH1A1POLBCYP1A2CYP3A4TSHR | |
| SCHEMBL305860 | 0.67 | ALDH1A1 (0.55) | ALDH1A1POLBSCN9AMAPTKDM4E | |
| SCHEMBL8381345 | 0.66 | MAP3K5 (0.36) | ALDH1A1POLBCYP1A2CYP3A4TSHR | |
| SCHEMBL146714 | 0.64 | NPC1 (0.56) | ALDH1A1POLBCYP1A2CYP3A4SCN9A | |
| SCHEMBL27955248 | 0.64 | SCN9A (0.40) | CYP1A2CYP3A4TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL3781174 | 0.63 | SCN9A (0.40) | CYP1A2CYP3A4TSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL2198674 | 0.63 | CRBN (0.63) | ALDH1A1POLBCYP3A4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044185-A2 | Imidazolidinone derivatives | ELI LILLY AND COMPANY (US) | 1982-01-20 | — | — | EP | disclosed |