SCHEMBL11290248

SCHEMBL11290248

CCc1c[nH]c(=O)n1-c1cc(C(C)(C)C)on1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTR7 P34969 1/20 0.35
EGFR P00533 3/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603308 0.66 HTR7 (0.38) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL6426953 0.65 GSK3A (0.41) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL11291880 0.64 MEN1 (0.37) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL27260273 0.64 MEN1 (0.39) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL11016605 0.63 HTR7 (0.43) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL11016579 0.63 HTR7 (0.43) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL11340429 0.62 ALOX15 (0.45) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL11017716 0.62 HTR7 (0.42) ALOX15MEN1KMT2AHTR7EGFR
SCHEMBL9610944 0.62 MEN1 (0.44) MEN1KMT2AEGFRALDH1A1HPGD
SCHEMBL17562978 0.62 ALOX15 (0.49) ALOX15MEN1KMT2AHTR7EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044185-A2 Imidazolidinone derivatives ELI LILLY AND COMPANY (US) 1982-01-20 EP disclosed