Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 11/20 | 0.41 |
| ▸ | GSK3B | P49841 | 11/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10802440 | 0.77 | RGS4 (0.40) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL6428649 | 0.74 | GSK3A (0.53) | GSK3AGSK3BMEN1KMT2AALDH1A1 | |
| SCHEMBL27260273 | 0.72 | MEN1 (0.39) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL10807029 | 0.67 | HTR7 (0.41) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL8796280 | 0.66 | HTR7 (0.43) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL10961593 | 0.66 | HTR7 (0.43) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL11290248 | 0.65 | ALOX15 (0.35) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL11016128 | 0.65 | HTR7 (0.44) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL11017716 | 0.65 | HTR7 (0.42) | HTR7MEN1KMT2AALOX15EGFR | |
| SCHEMBL10991348 | 0.64 | HTR7 (0.41) | HTR7MEN1KMT2AALOX15EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |
| EP-0129928-B1 | OXAZOLYL-SUBSTITUTED DIAZAHETEROCYCLES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-09-02 | — | — | EP | disclosed |
| EP-0129928-A1 | Oxazolyl-substituted diazaheterocycles | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-01-02 | — | — | EP | disclosed |
| US-4474598-A | HERBICIDES | SHELL OIL COMPANY (US) | 1984-10-02 | — | — | US | disclosed |