Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278754 | 0.89 | GAA (0.56) | LMNAGAAMAPK1CA12CA2 | |
| SCHEMBL11287133 | 0.79 | ALDH1A1 (0.50) | GAAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11283123 | 0.78 | KMT2A (0.62) | LMNAMAPK1KDM4EMEN1KMT2A | |
| SCHEMBL31046326 | 0.76 | LMNA (0.68) | LMNAGAAMAPK1TRPV1CA12 | |
| SCHEMBL11426226 | 0.75 | GBA1 (0.45) | KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL11282866 | 0.74 | GBA1 (0.55) | GAAKDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL11281560 | 0.73 | GBA1 (0.41) | MAPK1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL27979652 | 0.73 | CA12 (0.71) | LMNAGAAMAPK1TRPV1CA12 | |
| SCHEMBL11277846 | 0.71 | GPR183 (0.50) | GAAMAPT | |
| SCHEMBL11277852 | 0.71 | GPR183 (0.50) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |