Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278787 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2HSD17B10MAPTDHFR | |
| SCHEMBL11290070 | 0.86 | HSD17B10 (0.64) | ALDH1A1GAASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL11399909 | 0.82 | HTR2C (0.60) | ALDH1A1GAAGFERSMN1; SMN2HSD17B10 | |
| SCHEMBL11290550 | 0.79 | LMNA (0.57) | GAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL11283262 | 0.77 | KMT2A (0.50) | ALDH1A1ACHEKDM4EHPGDHTR3A | |
| SCHEMBL2922890 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GAAGFERSMN1; SMN2MAPT | |
| SCHEMBL11278102 | 0.75 | LMNA (0.56) | ALDH1A1GAASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL11289296 | 0.75 | HSD17B10 (0.45) | ALDH1A1SMN1; SMN2HSD17B10MAPTACHE | |
| SCHEMBL11280239 | 0.74 | HTR2C (0.64) | ALDH1A1SMN1; SMN2HSD17B10MAPTACHE | |
| SCHEMBL11284725 | 0.74 | NPC1 (0.58) | ALDH1A1SMN1; SMN2HSD17B10MAPTDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | claimed |
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |