Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | TGM1 | P22735 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13667153 | 0.93 | TPSAB1 (0.54) | TSHRALDH1A1GAATPSAB1TPSD1 | |
| SCHEMBL13668665 | 0.93 | TPSAB1 (0.54) | TSHRALDH1A1GAATPSAB1TPSD1 | |
| Tranexamic Acid SCHEMBL1129079 | 0.92 | ALDH1A1 (0.60) | TSHRALDH1A1GAATPSAB1TPSD1 | |
| SCHEMBL6350370 | 0.86 | ALDH1A1 (0.52) | TSHRALDH1A1GAAF13A1TGM2 | |
| SCHEMBL8393648 | 0.86 | LMNA (0.58) | TSHRALDH1A1GAATPSAB1TPSD1 | |
| SCHEMBL7418209 | 0.85 | TSHR (0.68) | TSHRALDH1A1GAATPSAB1TPSD1 | |
| SCHEMBL594858 | 0.85 | ALDH1A1 (0.67) | TSHRALDH1A1GAATPSAB1TPSD1 | |
| SCHEMBL594857 | 0.85 | ALDH1A1 (0.67) | TSHRALDH1A1GAATPSAB1TPSD1 | |
| SCHEMBL7403759 | 0.84 | MEN1 (0.54) | TSHRALDH1A1GAAF13A1TGM2 | |
| SCHEMBL7403761 | 0.84 | MEN1 (0.54) | TSHRALDH1A1GAAF13A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283020-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009143051-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |