Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329874 | 0.83 | LMNA (0.66) | ALDH1A1SMN1; SMN2LMNAHTTTP53 | |
| SCHEMBL13647029 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAHTTTP53 | |
| SCHEMBL13329971 | 0.78 | LMNA (0.64) | ALDH1A1SMN1; SMN2LMNAHTTTP53 | |
| SCHEMBL12674351 | 0.75 | METAP1 (0.60) | ALDH1A1SMN1; SMN2LMNAHTTCYP1A2 | |
| SCHEMBL13309780 | 0.73 | GBA1 (0.59) | ALDH1A1SMN1; SMN2TSHRCYP1A2HPGD | |
| SCHEMBL11507979 | 0.73 | LMNA (0.54) | ALDH1A1SMN1; SMN2LMNAHTTTP53 | |
| SCHEMBL13895143 | 0.73 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HTTCYP1A2KDM4E | |
| SCHEMBL16051361 | 0.71 | L3MBTL1 (0.47) | ALDH1A1KDM4EHPGDL3MBTL1HTR7 | |
| SCHEMBL16136909 | 0.71 | PIM1 (0.50) | ALDH1A1SMN1; SMN2MAPK1KDM4EHPGD | |
| SCHEMBL24008779 | 0.70 | LMNA (0.53) | ALDH1A1SMN1; SMN2LMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |