Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329874 | 0.88 | LMNA (0.66) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL13329901 | 0.86 | LMNA (0.81) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL13329965 | 0.83 | ESR1 (0.52) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL13329900 | 0.81 | KCNH3 (0.66) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL13329899 | 0.81 | KCNH3 (0.66) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL23788964 | 0.81 | TAAR1 (0.69) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL12340074 | 0.80 | MAPT (0.71) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL14918394 | 0.80 | MAPT (0.63) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL11291016 | 0.78 | ALDH1A1 (0.50) | LMNAMAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL9852822 | 0.77 | TAAR1 (0.64) | LMNAMAPTHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |