Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291983 | 0.83 | ALOX15 (0.37) | ALOX15POLBNR1H4L3MBTL1KMT2A | |
| SCHEMBL11288199 | 0.80 | ALOX15 (0.44) | ALOX15POLBL3MBTL1KMT2AAKR1C3 | |
| Hydrochloric Acid SCHEMBL11287384 | 0.79 | L3MBTL1 (0.52) | L3MBTL1KMT2ATDP1ATM | |
| SCHEMBL11283315 | 0.79 | ALOX15 (0.36) | ALOX15KMT2ATOP2A | |
| Alcohol SCHEMBL11286751 | 0.77 | ALOX15 (0.36) | ALOX15POLB | |
| SCHEMBL11288958 | 0.77 | ALOX15 (0.42) | ALOX15L3MBTL1KMT2ATDP1ATM | |
| SCHEMBL11290492 | 0.77 | ALOX15 (0.55) | ALOX15KMT2AAKR1C3TOP2A | |
| SCHEMBL11277015 | 0.77 | ALOX15 (0.55) | ALOX15KMT2AAKR1C3TOP2A | |
| SCHEMBL11290043 | 0.77 | ALOX15 (0.55) | ALOX15KMT2AAKR1C3TOP2A | |
| SCHEMBL11283358 | 0.77 | ALOX15 (0.55) | ALOX15KMT2AAKR1C3TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |