Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291986 | 0.87 | TOP1 (0.36) | ALOX15KMT2ATOP2ANPC1RAB9A | |
| SCHEMBL11291981 | 0.83 | ALOX15 (0.40) | ALOX15NR1H4POLBL3MBTL1KMT2A | |
| SCHEMBL11286759 | 0.81 | LMNA (0.38) | ALOX15KMT2AKDM4EALDH1A1 | |
| SCHEMBL11286755 | 0.80 | ALOX15 (0.34) | ALOX15POLBL3MBTL1KMT2ACNR2 | |
| SCHEMBL11286752 | 0.80 | ALOX15 (0.34) | ALOX15POLBL3MBTL1KMT2ACNR2 | |
| Hydrochloric Acid SCHEMBL11287387 | 0.79 | L3MBTL1 (0.51) | ALOX15L3MBTL1KMT2ANPC1ALDH1A1 | |
| SCHEMBL11283335 | 0.79 | TOP2A (0.36) | ALOX15NR1H4KMT2ATOP2ACNR2 | |
| SCHEMBL11286258 | 0.78 | ALOX15 (0.41) | ALOX15POLBKMT2ATOP2ANPC1 | |
| SCHEMBL11290055 | 0.78 | ALOX15 (0.51) | ALOX15KMT2ATOP2ANPC1RAB9A | |
| SCHEMBL11277018 | 0.78 | ALOX15 (0.51) | ALOX15KMT2ATOP2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |