SCHEMBL11292076

SCHEMBL11292076

Cc1ccc(C)c(N(CC(=O)O)C(=O)CSC(=O)C(C)(C)C)c1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11296877 0.90
SCHEMBL11297292 0.90 SMN1; SMN2 (0.33)
SCHEMBL11294511 0.88 ALDH1A1 (0.33)
SCHEMBL11271154 0.86 RAB9A (0.34)
SCHEMBL11290058 0.85 HDAC3 (0.31)
SCHEMBL11295914 0.85
SCHEMBL11482712 0.83 SMN1; SMN2 (0.32)
SCHEMBL11290011 0.83 MLYCD (0.33)
SCHEMBL11296934 0.81 KMT2A (0.50)
SCHEMBL11385222 0.81 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014167-B1 Aniline derivatives with antifungal activity and process for their preparation RHONE-POULENC AGROCHIMIE (FR) 1982-06-30 EP disclosed