Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.83 |
| ▸ | MMP1 | P03956 | 17/20 | 0.83 |
| ▸ | PGR | P06401 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598963 | 1.00 | NR3C1 (0.83) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL7592811 | 0.93 | NR3C1 (0.79) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL10599326 | 0.93 | NR3C1 (0.82) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL7547 | 0.93 | NR3C1 (0.83) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL6986508 | 0.93 | NR3C1 (0.83) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL11812693 | 0.93 | NR3C1 (0.83) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL7595137 | 0.92 | NR3C1 (0.80) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL11283914 | 0.92 | NR3C1 (0.78) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL1265487 | 0.92 | NR3C1 (0.82) | NR3C1MMP1PGRMEN1USP2 | |
| SCHEMBL147590 | 0.92 | NR3C1 (0.82) | NR3C1MMP1PGRMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000742-B1 | CORTICOIDS-17-ALKYLCARBONATES, PROCESS FOR THEIR PREPARATION AND PREPARATIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| EP-0000742-A1 | Corticoids-17-alkylcarbonates, process for their preparation and preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-21 | — | — | EP | disclosed |