Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.39 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292168 | 0.87 | LMNA (0.43) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL11766853 | 0.71 | LMNA (0.46) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL11292166 | 0.71 | LMNA (0.38) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL27475467 | 0.68 | GAA (0.53) | LMNAALDH1A1MEN1KMT2AIFNAR1 | |
| SCHEMBL5448135 | 0.66 | LMNA (0.69) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9342243 | 0.65 | CYP1A2 (0.45) | LMNAALDH1A1IFNAR1ADRB2ADRB1 | |
| SCHEMBL7265932 | 0.64 | IFNAR1 (0.43) | LMNAALDH1A1HPGDIFNAR1GAA | |
| SCHEMBL2116696 | 0.64 | IFNAR1 (0.43) | LMNAALDH1A1HPGDIFNAR1CYP1A2 | |
| SCHEMBL8474345 | 0.64 | IFNAR1 (0.47) | LMNAALDH1A1HPGDIFNAR1CYP2D6 | |
| SCHEMBL18217960 | 0.63 | IFNAR1 (0.42) | LMNAALDH1A1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |