Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292167 | 0.87 | LMNA (0.41) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL11292166 | 0.76 | LMNA (0.38) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL11766853 | 0.74 | LMNA (0.46) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL27475467 | 0.71 | GAA (0.53) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11583883 | 0.69 | ALDH1A1 (0.56) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL8737627 | 0.65 | PLK1 (0.66) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL7357489 | 0.64 | ANPEP (0.46) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL11762114 | 0.64 | KMT2A (0.43) | LMNAALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL12132477 | 0.63 | ANPEP (0.66) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL5448135 | 0.63 | LMNA (0.69) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |