Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 5/20 | 0.63 |
| ▸ | PGK1 | P00558 | 3/20 | 0.59 |
| ▸ | PGK2 | P07205 | 3/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745406 | 0.82 | MMP8 (0.50) | PTPN5PGK1PGK2MMP8MMP14 | |
| SCHEMBL11476691 | 0.80 | PGK1 (0.65) | PTPN5PGK1PGK2MMP8MMP14 | |
| SCHEMBL28980067 | 0.78 | MMP8 (0.47) | PTPN5PGK1PGK2MMP8MMP14 | |
| SCHEMBL8395379 | 0.78 | GRM8 (0.60) | PTPN5PGK1PGK2 | |
| SCHEMBL9007814 | 0.78 | PGK1 (0.56) | PTPN5PGK1PGK2MMP8MMP14 | |
| SCHEMBL11208020 | 0.78 | PGK1 (0.71) | PTPN5PGK1PGK2 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL292744 | 0.77 | PGK1 (0.59) | PTPN5PGK1PGK2MMP8MMP14 | |
| (4-Chlorophenyl)(Hydroxy)Methylphosphonic Acid SCHEMBL5746553 | 0.77 | PGK1 (0.59) | PTPN5PGK1PGK2MMP8MMP14 | |
| SCHEMBL2654115 | 0.73 | AHR (0.50) | — | |
| SCHEMBL11079769 | 0.72 | PGK1 (0.59) | PTPN5PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006205-B1 | PROCESS FOR THE PREPARATION OF CHLOROSTYRENECYCLOPROPANE CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |