Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30746068 | 1.00 | PRKCA (0.43) | PRKCAPRKCDGPR84CA2CA1 | |
| SCHEMBL3647097 | 0.98 | PRKCA (0.44) | PRKCAPRKCDGPR84CA2CA1 | |
| Hydrochloric Acid SCHEMBL28169807 | 0.96 | PRKCA (0.43) | PRKCAPRKCDGPR84CA2CA1 | |
| SCHEMBL2436142 | 0.92 | GPR84 (0.45) | GPR84CA2FFAR1MAPTZDHHC7 | |
| SCHEMBL22005296 | 0.92 | GPR84 (0.45) | GPR84CA2FFAR1MAPTZDHHC7 | |
| SCHEMBL15360245 | 0.92 | CA2 (0.50) | PRKCAPRKCDCA2CA1MAPT | |
| SCHEMBL5013944 | 0.92 | GPR84 (0.45) | GPR84CA2FFAR1MAPTZDHHC7 | |
| SCHEMBL21300541 | 0.92 | GPR84 (0.45) | GPR84CA2FFAR1MAPTZDHHC7 | |
| SCHEMBL11257974 | 0.92 | CA2 (0.50) | PRKCAPRKCDCA2CA1MAPT | |
| SCHEMBL5012509 | 0.92 | GPR84 (0.45) | GPR84CA2FFAR1MAPTZDHHC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151534-B | Inhibitors of interleukin-1 receptor associated kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof and methods of use thereof | 南京药石科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-4336402-A | Process for the preparation of N-alkyl-monosubstituted carbamic acid esters | ATLANTIC RICHFIELD COMPANY (US) | 1982-06-22 | — | — | US | disclosed |