⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129222 | 0.89 | — | — | |
| SCHEMBL1129458 | 0.80 | SRR (0.31) | — | |
| SCHEMBL27671106 | 0.74 | SRR (0.44) | — | |
| SCHEMBL1128675 | 0.71 | ADORA1 (0.30) | — | |
| SCHEMBL3172093 | 0.69 | — | — | |
| SCHEMBL27142298 | 0.66 | GBA1 (0.41) | — | |
| SCHEMBL38662183 | 0.65 | CCR1 (0.42) | — | |
| SCHEMBL1129269 | 0.63 | IGF1R (0.48) | — | |
| SCHEMBL1129220 | 0.63 | IGF1R (0.41) | — | |
| SCHEMBL1129455 | 0.61 | IGF1R (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283020-A1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |