SCHEMBL1129458

SCHEMBL1129458

NC(=O)OC(Cc1ccccc1)C1CCC(C2=C3C=NC=C[N+]3(Cl)C=N2)CC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SRR Q9GZT4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1129222 0.82
SCHEMBL1129271 0.80
SCHEMBL27671106 0.74 SRR (0.44) SRR
SCHEMBL27142298 0.67 GBA1 (0.41) SRR
SCHEMBL38662183 0.65 CCR1 (0.42) SRR
SCHEMBL1129455 0.63 IGF1R (0.37)
SCHEMBL1129220 0.61 IGF1R (0.41)
SCHEMBL1129383 0.61 USP2 (0.42)
SCHEMBL6636811 0.60 SRR (0.41) SRR
SCHEMBL2324493 0.60 MEN1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2283020-A1 SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES OSI Pharmaceuticals, Inc. (US) 2011-02-16 EP disclosed