Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296901 | 0.94 | LMNA (0.61) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11261223 | 0.89 | ABCB11 (0.59) | ABCB11LMNAMAPTMAPK1POLB | |
| SCHEMBL11296299 | 0.88 | MAPK1 (0.51) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11289986 | 0.88 | MAPT (0.65) | ABCB11LMNAMAPTMAPK1POLB | |
| SCHEMBL11299997 | 0.87 | LMNA (0.70) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11296975 | 0.86 | LMNA (0.54) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11296871 | 0.85 | ABCB11 (0.56) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11268845 | 0.85 | LMNA (0.61) | ABCB11LMNAMAPTMAPK1POLB | |
| SCHEMBL11297005 | 0.84 | LMNA (0.67) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11294309 | 0.81 | LMNA (0.82) | ABCB11LMNAMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |