Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299822 | 0.88 | ABCB11 (0.42) | ABCB11LMNAMAPTMAPK1SPHK1 | |
| SCHEMBL11296901 | 0.88 | LMNA (0.61) | ABCB11LMNAMAPTMAPK1SLC6A2 | |
| SCHEMBL11297976 | 0.87 | MAPT (0.41) | ABCB11LMNAMAPTMAPK1MME | |
| SCHEMBL11293008 | 0.85 | ABCB11 (0.61) | ABCB11LMNAMAPTMAPK1CHRM2 | |
| SCHEMBL11289986 | 0.84 | MAPT (0.65) | ABCB11LMNAMAPTMAPK1CHRM2 | |
| SCHEMBL11296990 | 0.83 | LMNA (0.39) | ABCB11LMNAMAPTMAPK1KMT2A | |
| SCHEMBL15258345 | 0.83 | ABCB11 (0.78) | ABCB11LMNAMAPTMAPK1HRH3 | |
| SCHEMBL7486243 | 0.83 | ABCB11 (0.42) | ABCB11LMNAMAPTMAPK1SLC6A2 | |
| SCHEMBL11299997 | 0.83 | LMNA (0.70) | ABCB11LMNAMAPTMAPK1SLC6A2 | |
| SCHEMBL11297005 | 0.81 | LMNA (0.67) | ABCB11LMNAMAPTMAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |