Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204801 | 0.87 | PDE2A (0.36) | TSHRMAPK1HIF1ACYP19A1AHR | |
| Hydrochloric Acid SCHEMBL8577339 | 0.84 | PDE2A (0.35) | TSHRMAPK1HIF1ACYP19A1IDO1 | |
| Hydrochloric Acid SCHEMBL8577343 | 0.84 | PDE2A (0.35) | TSHRMAPK1HIF1ACYP19A1IDO1 | |
| SCHEMBL11458379 | 0.82 | TSHR (0.52) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL5401000 | 0.79 | LMNA (0.50) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL809832 | 0.79 | LMNA (0.50) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL28777340 | 0.79 | CYP19A1 (0.55) | TSHRMAPK1HIF1ALMNACYP2A6 | |
| SCHEMBL11240836 | 0.79 | PDE2A (0.32) | TSHRMAPK1HIF1A | |
| SCHEMBL1508480 | 0.79 | ALDH1A1 (0.50) | TSHRAHR | |
| SCHEMBL196588 | 0.79 | CYP19A1 (0.55) | TSHRMAPK1HIF1ALMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004636-B1 | PROCESS FOR PREPARING BENZOTRIFLUORIDE AND ITS DERIVATIVES | Daikin Kogyo Co., Ltd. (JP) | 1982-07-07 | — | — | EP | disclosed |
| US-4242286-A | Process for preparing benzotrifluoride and its derivatives | DAIKIN KOGYO CO., LTD. (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4183873-A | WITH HYDROGEN FLUORIDE IN THE PRESENCE OF MOLYBDENUM PENTACHLORIDE CATALYST | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-01-15 | — | — | US | disclosed |
| EP-0004636-A2 | Process for preparing benzotrifluoride and its derivatives | Daikin Kogyo Co., Ltd. (JP) | 1979-10-17 | — | — | EP | disclosed |