Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 6/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.46 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.46 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204801 | 0.90 | PDE2A (0.36) | ALDH1A1TSHRKIF11CES2CES1 | |
| Hydrochloric Acid SCHEMBL8577339 | 0.87 | PDE2A (0.35) | ALDH1A1TSHRKIF11CES2CES1 | |
| Hydrochloric Acid SCHEMBL8577343 | 0.87 | PDE2A (0.35) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL63468 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL10672363 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL1539075 | 0.81 | TSHR (0.50) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL4471260 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL11598948 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL11240836 | 0.81 | PDE2A (0.32) | ALDH1A1TSHRKIF11 | |
| SCHEMBL11599184 | 0.81 | TSHR (0.50) | ALDH1A1TSHRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093669-A | HALOGEN TRANSFER CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | claimed |
| EP-1940769-B1 | DICARBOXYLIC ACID DERIVATIVES AND THEIR USE | BAYER IP GMBH (DE) | 2016-08-10 | — | — | EP | disclosed |
| EP-2289868-B1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2014-08-13 | — | — | EP | disclosed |
| US-8222281-B2 | Carboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| CN-102076650-A | Carboxylic acid compound | DAIICHI SANKYO CO LTD | 2011-05-25 | — | — | CN | disclosed |
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |
| US-4849557-A | Preparation of trifluoromethyltoluene from halomethylbenzotrifluoride | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-07-18 | — | — | US | disclosed |
| US-4093669-A | HALOGEN TRANSFER CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4079089-A | CONTACTING A BIS/TRICHLOROMETHYL/-BENZENE WITH HYDROGEN FLUORIDE, HALOGEN TRANSFER CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | AKR1C3, SLC5A1, GPR119 | ALDH1A1 195/4885TSHR 846/4885KIF11 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.