Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.72 |
| ▸ | USP2 | O75604 | 7/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.72 |
| ▸ | PGR | P06401 | 5/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | CNR1 | P21554 | 2/20 | 0.72 |
| ▸ | AR | P10275 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285613 | 0.92 | CYP3A4 (0.72) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL11291108 | 0.91 | NR3C1 (0.72) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL11292765 | 0.91 | CYP3A4 (0.76) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL11291837 | 0.91 | CYP3A4 (0.73) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL11304364 | 0.91 | CYP3A4 (0.75) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL1217308 | 0.91 | CYP3A4 (0.77) | CYP3A4USP2NR3C1PGRADORA3 | |
| Water SCHEMBL1219475 | 0.90 | CYP3A4 (0.76) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL8832311 | 0.87 | CYP3A4 (0.81) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL13524493 | 0.87 | CYP3A4 (0.83) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL102220 | 0.87 | CYP3A4 (0.83) | CYP3A4USP2NR3C1PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000742-B1 | CORTICOIDS-17-ALKYLCARBONATES, PROCESS FOR THEIR PREPARATION AND PREPARATIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0000742-A1 | Corticoids-17-alkylcarbonates, process for their preparation and preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-21 | — | — | EP | disclosed |