Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.77 |
| ▸ | USP2 | O75604 | 7/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.77 |
| ▸ | PGR | P06401 | 6/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.77 |
| ▸ | CNR1 | P21554 | 2/20 | 0.77 |
| ▸ | AR | P10275 | 2/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1219475 | 0.99 | CYP3A4 (0.76) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL8832311 | 0.96 | CYP3A4 (0.81) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL102220 | 0.95 | CYP3A4 (0.83) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL5516980 | 0.92 | CYP3A4 (0.81) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL20485505 | 0.91 | NR3C1 (0.78) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL7271 | 0.91 | NR3C1 (0.78) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL11293441 | 0.91 | CYP3A4 (0.72) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL13524493 | 0.90 | CYP3A4 (0.83) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL4174889 | 0.90 | NR3C1 (0.77) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL4929631 | 0.90 | CYP3A4 (0.77) | CYP3A4USP2NR3C1PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149439-B2 | Multi-particulate, modified-release composition | SANDOZ AG (CH) | 2015-10-06 | — | — | US | claimed |
| WO-2006102446-A2 | MULTI-PARTICULATE, MODIFIED-RELEASED COLONIC COMPOSITION | SANDOZ AG (CH) | 2006-09-28 | — | — | WO | claimed |
| US-20060210631-A1 | Multi-particulate, modified-release composition | SANDOZ AG (CH) | 2006-09-21 | — | — | US | claimed |
| US-5897878-A | ORALLY ADMINISTERING DELIVERY SYSTEM IN WHICH FLUID IMBIBITION CAUSES HYDROPHILIC POLYMER TO AGGREGATE IN SITU IN PRESENCE OF POLYHYDROXY COMPOUND AND CAUSES PUSH LAYER TO ABSORB FLUID AND DELIVER AGGREGATES CONTAINING STEROID | ALZA CORPORATION (US) | 1999-04-27 | — | — | US | claimed |
| US-5650170-A | Dosage form for delivering drug at a controlled rate to the intestine and to the colon | ALZA CORPORATION (US) | 1997-07-22 | — | — | US | claimed |
| EP-0521074-B1 | DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE | ALZA CORP (US) | 1994-03-02 | — | — | EP | claimed |
| US-5215965-A | Administering corticosteroid and at least one serine protease inhibitor, its salt or derivatives which bind with the mediators of mast or T-cells | SONORAN DESERT CHEMICALS CORP. LLC | 1993-06-01 | — | — | US | claimed |
| US-5178866-A | DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE | ALZA CORPORATION (US) | 1993-01-12 | — | — | US | claimed |
| EP-0521074-A1 | DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE. | ALZA CORP (US) | 1993-01-07 | — | — | EP | claimed |
| WO-1991014426-A1 | DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE | ALZA CORPORATION (US) | 1991-10-03 | — | — | WO | claimed |
| CN-118973574-A | Use of ibudilast for treating sequela of new coronaries pneumonia | 美迪诺亚公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-112410298-A | Enhanced stem cell compositions | 菲特治疗公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112375734-A | Enhanced stem cell compositions | 菲特治疗公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-104066837-B | Enhanced stem cell compositions | 菲特治疗公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-111788185-A | Diaryl substituted 6,5 fused ring compounds as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2020-10-16 | — | — | CN | disclosed |
| WO-1992004011-A1 | DOSAGE FORM FOR TIME-VARYING PATTERNS OF DRUG DELIVERY | ALZA CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1991014426-A1 | DOSAGE FORM FOR DELIVERING DRUG TO THE INTESTINE | ALZA CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |
| US-4904474-A | Delivery of drug to colon by oral disage form | ALZA CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0097651-A1 | DELAYED RELEASE ORAL DOSAGE FORMS CONTAINING 5-ASA. | TILLOTT J B LTD (GB) | 1984-01-11 | — | — | EP | disclosed |
| WO-1983000435-A1 | ORALLY ADMINISTRABLE PHARMACEUTICAL COMPOSITIONS | RHODES, JOHN | 1983-02-17 | — | — | WO | disclosed |