Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294563 | 0.88 | ABCB11 (0.73) | ABCB11LMNAMAPTMAPK1EPHX2 | |
| SCHEMBL11295569 | 0.86 | KDM4E (0.47) | ABCB11LMNAMAPTMAPK1EPHX2 | |
| SCHEMBL11290182 | 0.85 | KDM4E (0.48) | ABCB11LMNAMAPTMAPK1EPHX2 | |
| SCHEMBL11292673 | 0.85 | MAPT (0.65) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL15258345 | 0.84 | ABCB11 (0.78) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL11289014 | 0.79 | MAPT (0.70) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL11290903 | 0.79 | MAPT (0.53) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL11292357 | 0.77 | LMNA (0.60) | ABCB11LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL11297133 | 0.77 | MTNR1A (0.51) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL11289835 | 0.76 | LMNA (0.54) | ABCB11LMNAMAPTMAPK1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |